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Papers in refereed journals

2010

[77]

Design, synthesis and in vitro antimalarial evaluation of triazole-linked chalcone and dienone hybrid compounds. E. M. Guantai, K. Ncokazi a, T. J. Egan, J. Gut, P. J. Rosenthal, P. J. Smith, and K. Chibale*. Bioorg. Med. Chem. 2010, 18, 8243-8256.

[76]

Novel Tetracyclic Structures from the Synthesis of Thiolactone-Isatin Hybrids. R. H. Hans, H. Su and K. Chibale*. Belstein Journal of Organic Chemistry 2010, 6,(78), 1-7 ( doi: 10.3762/bjoc.6.78).

[75]

Synthesis and in vitro evaluation of gold(I) thiosemicarbazone complexes for antimalarial activity. S.D. Khanye, G. Smith, J. Gut, P. J. Rosenthal and K. Chibale*. Journal of Inorganic Biochemistry 2010, 104, 1079-1083.

[74]

Cyclopalladated Complexes Containing Tridentate Thiosemicarbazone Ligands of Biological Significance: Synthesis, Structure and Antimalarial activity. P. Chellan, S. Nasser, K. Chibale, G. S. Smith*. Journal of Organometallic Chemistry. 2010, 695, 2225-2232.

[73]

Synthesis, structures and in vitro biological screening of palladium(II) complexes of functionalised salicylaldimine thiosemicarbazones as antimalarial and anticancer agents. P. Chellan, N. Shunmoogam-Gounden, D.T. Hendricks, J.Gut, P. J. Rosenthal, C. Lategan, P. J. Smith, K. Chibale, G.S. Smith*. Eur.J. Inorg. Chem. 2010, 3520-3528.

[72]

Thiosemicarbazone Salicylaldiminato Palladium(II)-Catalyzed Mizoroki-Heck Reactions. G. Xie, P. Chellan, J. Mao*, K. Chibale, G. S. Smith* Advanced Synthesis & Catalysis 2010, 352, 1641-1647.

[71]

CRIMALDDI: a co-ordinated, rational, and integrated effort to set logical priorities in antimalarial drug discovery initiatives. I. C Boulton*, S. Nwaka, I. Bathurst, M. Lanzer, D. Taramelli, H. Vial, C. Doerig, S. M. N. Efange, K. Chibale & S.A. Ward* Malaria Journal. 2010, 9, 202.

[70]

Chloroquine resistance: proposed mechanisms and countermeasures. E. M. Guantai and K. Chibale*. Current Drug Delivery. 2010, 7, 312-323.

[69]

Comparison of the Antiplasmodial and Falcipain-2 Inhibitory Activity of β-Amino Alcohol Thiolactone-Chalcone and Isatin-Chalcone Hybrids. R.H. Hans, J. Gut, P.J. Rosenthal, and K. Chibale* Bioorg. Med. Chem. Lett. 2010, 20, 2234-2237.

[68]

Gold (I) Derived Thiosemicarbazone Complexes with rare halogen-halogen interaction-Reduction of [Au(damp-C1,N)Cl2], S. Khanye; N. B. Bathori, G. S. Smith, and K. Chibale*. Dalton Transactions, 2010, 39 (10), 2697 - 2700.

[67]

Synthesis, Antimalarial and Antitubercular Activity of Acetylenic Chalcones. R.H. Hans; E.M Guantai.; C. Lategan; P.J Smith,; B. Wan.; S.G Franzblau.; J. Gut; P. J Rosenthal, and K. Chibale*. Bioorg. Med. Chem. Lett. 2010, 20, 942-944. Article recognised as a "Top 25 Most-Cited Article 2010 - 2011".

[66]

Synthesis and evaluation of phenylequine for antimalarial activity in vitro and in vivo. M.A.L. Blackie, V. Yardley, and K. Chibale*. Bioorg. Med. Chem. Lett. 2010, 20, 1078-1080.